STE14 / YDR410C Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

Non-essential gene; null mutant of ‘a’ mating type is sterile; null mutant fails to methylate a-factor, Ras1p, or Ras2p; null mutant displays defective export of a-factor; overexpression causes proliferation of the nuclear inner membrane; in large-scale studies, null mutation confers shorter chronological lifespan and sensitivity to myriocin and CG-1521; diploid heterozygous null mutant is sensitive to starvation

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources