Sequence Help

CIA1 / YDR267C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

Protein Product
iron-sulfur cluster assembly protein CIA1
Feature Type
ORF , Verified
Component of cytosolic iron-sulfur protein assembly (CIA) machinery; acts at late step of Fe-S cluster assembly; forms CIA targeting complex with Cia2p and Met18p that directs Fe-S cluster incorporation and maturation of a subset of cytosolic and nuclear proteins involved in methionine biosynthesis, DNA replication and repair, transcription and telomere maintenance; contains WD40 repeats; human homolog CIAO1 complements the yeast cia1 null mutant 1 2 3 4