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SIR4 / YDR227W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
ASD1 , STE9 , UTH2
Protein Product
chromatin-silencing protein SIR4
Feature Type
ORF , Verified
Description
SIR protein involved in assembly of silent chromatin domains; silent information regulator (SIR) along with SIR2 and SIR3; involved in assembly of silent chromatin domains at telomeres and the silent mating-type loci; some alleles of SIR4 prolong lifespan; required for telomere hypercluster formation in quiescent yeast cells 2 3 4 5

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