Sequence Help
HST4 / YDR191W Sequence
Sequences and genome annotation information for Reference Strain S288C and a select set of
Alternative References.
- Protein Product
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NAD-dependent histone deacetylase HST4
- Feature Type
- ORF
, Verified
- Description
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NAD(+)-dependent protein deacetylase; deacetylation targets are primarily mitochondrial proteins; involved along with Hst3p in silencing at telomeres, cell cycle progression, radiation resistance, genomic stability and short-chain fatty acid metabolism; accumulates in mitochondria in response to biotin starvation and may link biotin metabolism with energy homeostasis; member of the Sir2 family and may be the functional equivalent of human SIRT3
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