Phenotype Help

RPA14 / YDR156W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.



Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

59 entries for 26 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
anaerobic growth: decreased
systematic mutation setnull
Allele: rpa14-Δ
S288CTreatment: anoxia
Details: poor growth as indicated by measurements of colony size
Samanfar B, et al. (2013) PMID:23467670
cell cycle progression in G1 phase: abnormal
systematic mutation setoverexpressionS288CDetails: accumulation of cells with a 1C DNA content and an increased percentage of unbudded cells, indicative of a G1 phase delay or arrest
Niu W, et al. (2008) PMID:18617996
cell size: decreased
systematic mutation set

analysis of cell size for mutants in the systematic deletion collection

null
Allele: rpa14-Δ
S288CDetails: mutant is among the smallest 5% of haploid deletion strains
Jorgensen P, et al. (2002) PMID:12089449
chemical compound accumulation: abnormal
systematic mutation setnull
Allele: rpa14-Δ
S288C alpha-amino acidDetails: Significantly altered free amino acid profile (X^2- test p < 0.01)
Mülleder M, et al. (2016) PMID:27693354
chromosome/plasmid maintenance: abnormal
homozygous diploidnull
Allele: rpa14-Δ
S288CDetails: loss of heterozygosity at the MET15 locus increased 2-6 fold, but not changed at MAT or SAM2 loci
Andersen MP, et al. (2008) PMID:18562670
chronological lifespan: increased
competitive growth

competitive survival of stationary phase co-cultures

null
Allele: rpa14-Δ
S288CGaray E, et al. (2014) PMID:24586198
competitive fitness: decreased
homozygous diploid, competitive growth

genome-wide fitness profiling

null
Allele: rpa14-Δ
S288CMedia: YPD
Details: Relative fitness score: 0.918
Deutschbauer AM, et al. (2005) PMID:15716499
competitive fitness: decreased
systematic mutation set

fitness profiling after 5 generations

null
Allele: rpa14-Δ
S288CMedia: synthetic medium, synthetic complete - trp medium
Giaever G, et al. (2002) PMID:12140549
competitive fitness: decreased
competitive growth

fitness profiling using complete deletion alleles

null
Allele: rpa14-Δ
S288CMedia: minimal medium
Details: Relative fitness score: 0.875
Breslow DK, et al. (2008) PMID:18622397
competitive fitness: decreased
systematic mutation setnull
Allele: rpa14-Δ
S288CMedia: synthetic complete medium, SC
Qian W, et al. (2012) PMID:23103169
Showing 1 to 10 of 59 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


Reset

Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.


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