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TAF12 / YDR145W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

TAF61 21 , TAF68 , TafII68 , TafII61
Feature Type
ORF , Verified
Subunit (61/68 kDa) of TFIID and SAGA complexes; involved in RNA polymerase II transcription initiation and in chromatin modification, similar to histone H2A; overexpression of the human ortholog, TAF12, an oncogene involved in the formation of choroid plexus carcinomas, results in dosage chromosomal instability (dCIN) in a human cell line similar to the dCIN observed in yeast overexpressors 1 2 3 4