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YCF1 / YDR135C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

Protein Product
ATP-binding cassette glutathione S-conjugate transporter YCF1
Feature Type
ORF , Verified
Vacuolar glutathione S-conjugate transporter; ABC-C transporter of the ATP-binding cassette family; required for vacuole fusion; forms stable complexes with vacuole fusion machinery; regulates Vam7p recruitment to vacuoles; role in detoxifying metals (Cd, Hg, As); transports GSSG that is not immediately reduced in cytosol to vacuole; transports unconjugated bilirubin, selenodigluthatione, oxidized glutathione; similar to human cystic fibrosis protein CFTR 1 2 3 4 5 6 7 8
EC Number,