Sequence Help

MTC5 / YDR128W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
SEA3 2
Feature Type
ORF , Verified
Description
Subunit of SEACAT, a subcomplex of the SEA complex; Mtc1p, along with Rtc1p and Sea4p, redundantly inhibit the TORC1 inhibitory role of the Iml1p/SEACIT (Iml1p-Npr2p-Npr3p) subcomplex, a GAP for GTPase Gtr1p (EGOC subunit) in response to amino acid limitation, thereby resulting in activation of TORC1 signaling; SEA is a coatomer-related complex that associates dynamically with the vacuole; relative distribution to the vacuolar membrane decreases upon DNA replication stress 2 3 4

Resources