Phenotype Help

UBC13 / YDR092W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.



Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

53 entries for 17 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
bud morphology: abnormal
systematic mutation setnull
Allele: ubc13-Δ
S288CDetails: bud is abnormally elongated
Watanabe M, et al. (2009) PMID:19466415
chemical compound accumulation: increased
homozygous diploid null
Allele: ubc13-Δ
S288C cobalt(2+)Treatment: cobalt dichloride, 1 mM
Details: cobalt sensitive null mutant accumulates cobalt after treatment with CoCl2 for 12 hrs
Zhao YY, et al. (2020) PMID:31904504
chemical compound accumulation: increased
homozygous diploid null
Allele: ubc13-Δ
S288C reactive oxygen speciesTreatment: cobalt dichloride, 1 mM
Details: increased intracellular accumulation of ROS in cells treated with CoCl2 for 12 hrs; possible defect in scavenging oxidative stress
Zhao YY, et al. (2020) PMID:31904504
chemical compound excretion: increased
systematic mutation setnull
Allele: ubc13-Δ
S288C inositolMedia: synthetic medium lacking inositol and choline
Details: Opi- phenotype; overproduction and excretion of inositol in the absence of inositol and choline
Hancock LC, et al. (2006) PMID:16582425
colony sectoring: increased
heterozygous diploid, systematic mutation setnull
Allele: ubc13-Δ
S288CAssay: quantitative chromosome transmission fidelity (qCTF) assay
Details: >1.5 fold increase in mini-chromosome loss relative to wt, indicative of chromosome instability (CIN)
Zhu J, et al. (2015) PMID:25823586
competitive fitness: increased
competitive growth

fitness profiling using complete deletion alleles

null
Allele: ubc13-Δ
S288CMedia: minimal medium
Details: Relative fitness score: 1.007
Breslow DK, et al. (2008) PMID:18622397
competitive fitness: increased
homozygous diploid, competitive growthnull
Allele: ubc13-Δ
S288CTreatment: conditions that mimic Phase I of a batch fermentation, equivalent to ~14 hours after inoculation of a batch fermentation
Novo M, et al. (2013) PMID:24040173
competitive fitness: increased
homozygous diploid, competitive growthnull
Allele: ubc13-Δ
S288CTreatment: conditions that mimic Phase II of a batch fermentation, equivalent to ~22 hours after inoculation of a batch fermentation
Novo M, et al. (2013) PMID:24040173
heat sensitivity: decreased
classical genetics overexpressionS288CTemperature: elevated temperature, 39 °C
Hiraishi H, et al. (2006) PMID:17090950
heat sensitivity: decreased
systematic mutation set

high throughput heat ramp cell death assay

null
Allele: ubc13-Δ
S288CTemperature: elevated temperature
Details: ramp temperature from ambient to 30 deg C immediately, hold 1 min at 30 deg C, ramp temperature from 30 deg C to 62 deg C over 20 min, return to ambient
Teng X, et al. (2011) PMID:21814286
Showing 1 to 10 of 53 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


Reset

Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.


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