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DOA4 / YDR069C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
DOS1 3 , MUT4 7 , NPI2 8 9 , SSV7 10 , UBP4 11
Protein Product
ubiquitin-specific protease DOA4
Feature Type
ORF , Verified
Description
Ubiquitin hydrolase; deubiquitinates intralumenal vesicle (ILVs) cargo proteins; required for recycling ubiquitin from proteasome-bound ubiquitinated intermediates, acts at the late endosome/prevacuolar compartment to recover ubiquitin from ubiquitinated membrane proteins destined for the vacuole; DOA4 has a paralog, UBP5, that arose from the whole genome duplication 2 3 4 5 6
Paralog
UBP5 5
EC Number
3.4.19.12

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