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CDC34 / YDR054C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
DNA6 51 52 , UBC3 8
Protein Product
SCF E2 ubiquitin-protein ligase catalytic subunit CDC34
Feature Type
ORF , Verified
Description
Ubiquitin-conjugating enzyme (E2); catalytic subunit of SCF ubiquitin-protein ligase complex (together with Skp1p, Rbx1p, Cdc53p, and an F-box protein) that regulates cell cycle progression by targeting key substrates for degradation; protein abundance increases in response to DNA replication stress; human CDC34 functionally complements the thermosensitivity of the cdc34-2 mutant 2 3 4
EC Number
2.3.2.23

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