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DBF4 / YDR052C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

DNA52 22 , LSD7
Protein Product
protein serine/threonine kinase activating protein DBF4
Feature Type
ORF , Verified
Regulatory subunit of Cdc7p-Dbf4p kinase complex; required for Cdc7p kinase activity and initiation of DNA replication; phosphorylates the Mcm2-7 family of proteins; cell cycle regulated; relative distribution to the nucleus increases upon DNA replication stress; co-expression of human CDC7 and DBF4 complements single cdc7 or dbf4 null mutations or the cdc7 dbf4 double null mutation 2 3 4 5