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TPI1 / YDR050C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Protein Product
triose-phosphate isomerase TPI1
Feature Type
ORF , Verified
Description
Triose phosphate isomerase, abundant glycolytic enzyme; mRNA half-life is regulated by iron availability; transcription is controlled by activators Reb1p, Gcr1p, and Rap1p through binding sites in the 5' non-coding region; inhibition of Tpi1p activity by PEP (phosphoenolpyruvate) stimulates redox metabolism in respiring cells; E104D mutation in human homolog TPI1 causes a rare autosomal disease; human TPI1 can complement yeast null mutant 1 2 3 4 5 6
EC Number
5.3.1.1

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