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NSI1 / YDR026C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

YTT1 6
Feature Type
ORF , Verified 2
RNA polymerase I termination factor; binds to rDNA terminator element, required for efficient Pol I termination; required for rDNA silencing at NTS1; facilities association of Sir2p with NTS1, contributes to rDNA stability and cell longevity; interacts physically with Fob1p and RENT subunits, Sir2p and Net1p; may interact with ribosomes, based on co-purification experiments; Myb-like DNA-binding protein; NSI1 has a paralog, REB1, that arose from the whole genome duplication 1 2 3 4 5
REB1 5