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CDC13 / YDL220C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
EST4 27
Protein Product
telomere-binding protein CDC13
Feature Type
ORF , Verified
Description
Single stranded DNA-binding protein found at TG1-3 telomere G-tails; key roles in regulation of telomerase, telomere end protection, conventional telomere replication; regulates telomere replication through recruitment of specific sub-complexes, essential function is telomere capping; forms homodimer via N-terminus; disruption of dimerization leads to short telomeres; autophagy and proteasome are involved in Cdc13p degradation; differentially phosphorylated through cell cycle 3 5 6 7

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