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PPH22 / YDL188C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
PPH2 8
Protein Product
phosphoprotein phosphatase 2A catalytic subunit PPH22
Feature Type
ORF , Verified
Description
Catalytic subunit of protein phosphatase 2A, PP2A; functionally redundant with Pph21p; C-terminally methylated; forms alternate complexes with several regulatory subunits; involved in signal transduction and regulation of mitosis; protein abundance increases in response to DNA replication stress; dephosphorylates Tel1p/Mec1p-phosphorylated Cdc13p to promote telomerase release from telomeres at G2/M; PPH22 has a paralog, PPH21, that arose from the whole genome duplication 1 2 3 4 5 6 7
Paralog
PPH21 6
EC Number
3.1.3.16

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