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CDC48 / YDL126C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Protein Product
AAA family ATPase CDC48
Feature Type
ORF , Verified
Description
AAA ATPase with protein-unfoldase activity; subunit of polyUb-selective segregase complex involved in ERAD, INM-associated degradation (INMAD), mitotic spindle disassembly, macroautophagy, PMN, ribosome-associated degradation, ribophagy, homotypic ER membrane fusion, SCF complex disassembly, cell wall integrity, and telomerase regulation; mobilizes membrane-anchored transcription factors by regulated Ub/proteasome-dependent processing (RUP); human ortholog VCP complements a cdc48 mutant 2 3 4 5 6 7 8 9 10 11 12 13 14
EC Number
3.6.4.6

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