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KIN28 / YDL108W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Protein Product
TFIIH complex serine/threonine-protein kinase subunit KIN28
Feature Type
ORF , Verified
Description
Ser/Thr protein kinase and subunit of TFIIK, a TFIIH subassembly; phosphorylates the C-terminal domain (CTD) of RNAPII (Ser5 and Ser7); facilitates recruitment of mRNA 5'-capping and polyadenylation factors to the RNAPII holoenzyme complex; minor role in RNAPII transcription; role in RNAPI transcription; regulates Atg1p kinase complex assembly during nitrogen starvation induced autophagy; associates with cyclin Ccl1p; relocalizes to the cytosol in response to hypoxia; ortholog of human CDK7 2 3 4 5 6 7 8 9
EC Number
2.7.11.23

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