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VAM6 / YDL077C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
CVT4 12 , VPL18 13 , VPL22 14 , VPS39 13 15
Feature Type
ORF , Verified
Description
Guanine nucleotide exchange factor for the GTPase Gtr1p; subunit of the HOPS endocytic tethering complex; vacuole membrane protein; functions as a Rab GTPase effector, interacting with both GTP- and GDP-bound conformations of Ypt7p; facilitates tethering and promotes membrane fusion events at the late endosome and vacuole; required for both membrane and protein trafficking; component of vacuole-mitochondrion contacts (vCLAMPs) important for lipid transfer between organelles 2 3 4 5 6 7 8 9 10 11

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