Phenotype Help

LHP1 / YDL051W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.



Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

57 entries for 17 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
alkaline pH resistance: increased
systematic mutation set reduction of function
Allele: lhp1-S19A
S288CTreatment: pH 8.5
Viéitez C, et al. (2022) PMID:34663920
anaerobic growth: increased
systematic mutation set reduction of function
Allele: lhp1-S19A
S288CViéitez C, et al. (2022) PMID:34663920
competitive fitness: decreased
systematic mutation setnull
Allele: lhp1-Δ
S288CMedia: synthetic oak exudate medium, OAK
Qian W, et al. (2012) PMID:23103169
competitive fitness: increased
competitive growth

fitness profiling using complete deletion alleles

null
Allele: lhp1-Δ
S288CMedia: minimal medium
Details: Relative fitness score: 1.021
Breslow DK, et al. (2008) PMID:18622397
competitive fitness: increased
systematic mutation setnull
Allele: lhp1-Δ
S288C ethanolQian W, et al. (2012) PMID:23103169
competitive fitness: increased
systematic mutation setnull
Allele: lhp1-Δ
S288CMedia: synthetic complete medium, SC
Qian W, et al. (2012) PMID:23103169
heat sensitivity: increased
systematic mutation set reduction of function
Allele: lhp1-S19A
S288CTemperature: elevated temperature, 42 °C
Viéitez C, et al. (2022) PMID:34663920
invasive growth: increased
homozygous diploid, systematic mutation setoverexpressionSigma1278bMedia: nitrogen-sufficient medium
Details: agar invasion score: 0.94; enhanced pseudohyphal growth, based on elevated invasiveness
Shively CA, et al. (2013) PMID:23410832
metal resistance: decreased
systematic mutation setreduction of function
Allele: lhp1-S19A
S288C2 mM nickel sulfateViéitez C, et al. (2022) PMID:34663920
metal resistance: decreased
systematic mutation setreduction of function
Allele: lhp1-S259A
S288C3 mM copper(II) sulfateViéitez C, et al. (2022) PMID:34663920
Showing 1 to 10 of 57 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


Reset

Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.


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