Phenotype Help

PMP2 / YEL017C-A Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.



Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

8 entries for 7 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
competitive fitness: decreased
systematic mutation setnull
Allele: pmp2-Δ
S288CMedia: synthetic complete medium, SC
Qian W, et al. (2012) PMID:23103169
competitive fitness: increased
competitive growth

fitness profiling using complete deletion alleles

null
Allele: pmp2-Δ
S288CMedia: minimal medium
Details: Relative fitness score: 1.005
Breslow DK, et al. (2008) PMID:18622397
lifespan: increased
systematic mutation setnull
Allele: pmp2-Δ
S288CMedia: cells stored on YPD plates at 4 deg C for 5 years
Details: hibernating lifespan extended
Postma L, et al. (2009) PMID:20157578
resistance to chemicals: decreased
systematic mutation setnull
Allele: pmp2-Δ
S288C0.4% (w/v), pH 4.3 acetic acidKawahata M, et al. (2006) PMID:16911514
resistance to chemicals: decreased
systematic mutation set null
Allele: pmp2-Δ
S288C4 ng/ml sirolimusDetails: sirolimus is rapamycin
Nicastro R, et al. (2021) PMID:33690632
utilization of nitrogen source: decreased rate
systematic mutation set

prototrophic version of yeast deletion collection

null
Allele: pmp2-Δ
S288C arginineVanderSluis B, et al. (2014) PMID:24721214
vegetative growth: decreased rate
classical geneticsoverexpressionS288CDetails: "genetic tug-of-war" method to identify dosage-sensitive genes by measuring the copy number limit for a plasmid carrying the gene with its normal regulatory sequences
Makanae K, et al. (2013) PMID:23275495
viable
systematic mutation setnull
Allele: pmp2-Δ
S288CGiaever G, et al. (2002) PMID:12140549
Showing 1 to 8 of 8 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


Reset

Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.


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