Sequence Help

TIF1 / YKR059W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
eIF4A
Protein Product
translation initiation factor eIF4A
Feature Type
ORF , Verified
Description
Translation initiation factor eIF4A; DEAD-box RNA helicase that couples ATPase activity to mRNA binding and unwinding; ATP hydrolysis accelerates the recruitment of mRNA during 48S preinitiation complex (PIC) assembly; ATPase activity stimulated by either eIF4G1 or by the PIC in an eIF3g and eIFGi subunit-dependent manner, independent of eIF4E and eIF4G; subunit of the mRNA cap-binding protein complex (eIF4F) with eIF4E and eIF4G; protein abundance increases in response to DNA replication stress 3 4 5 6 7 8 9 10
Paralog
TIF2

Resources