Sequence Help

MIA40 / YKL195W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

TIM40 7 , FMP15
Feature Type
ORF , Verified
Import and assembly protein in mitochondrial intermembrane space; component of MIA pathway which mediates import and oxidative folding of substrates including small proteins containing twin cysteine motifs; acts in concert with Erv1p, which oxidizes the cysteine residues of Mia40p to comprise a disulfide relay system that catalyzes import; also mediates folding of Atp23p via a chaperone-like activity; forms a dimer that binds iron-sulfur cluster in vitro 1 2 3 4 5 6