Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.
A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.
29 entries for 17 phenotypesIncrease the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.
| Phenotype | Experiment Type | Mutant Information | Strain Background | Chemical | Details | Reference |
|---|---|---|---|---|---|---|
| actin cytoskeleton morphology: abnormal | classical genetics | null Allele: hym1-Δ | W303 | Treatment: alpha-factor Details: decrease in the quantity of cells (~70%) with polarized actin cortical patches at the tip of the mating projection compared to wild-type cells (~98%) | Nelson B, et al. (2003) PMID:12972564 | |
| axial budding pattern: decreased | classical genetics | null Allele: hym1-Δ | W303 | Details: increased random budding pattern in a W303 derivative expressing BUD4 to correct an axial budding defect | Nelson B, et al. (2003) PMID:12972564 | |
| bipolar budding pattern: decreased | homozygous diploid | null Allele: hym1-Δ | W303 | Details: increased random budding pattern in a W303 derivative expressing BUD4 | Nelson B, et al. (2003) PMID:12972564 | |
| cell shape: abnormal | homozygous diploid | null Allele: hym1-Δ | S288C | Details: cells are rounder than wild-type diploids which are oval shaped | Bidlingmaier S, et al. (2001) PMID:11259593 | |
| cell shape: abnormal | classical genetics | null Allele: hym1-Δ | S288C | Details: round-shaped morphology rather than ellipsoidal | Nelson B, et al. (2003) PMID:12972564 | |
| colony appearance: abnormal | homozygous diploid | null Allele: hym1-Δ | W303 | Details: scalloped colony edges and roughened surface; phenotype observed in both native W303 background (bud4) and W303 BUD4+ | Voth WP, et al. (2005) PMID:15947194 | |
| colony appearance: abnormal | classical genetics | null Allele: hym1-Δ | W303 | Details: scalloped colony edges and roughened surface; phenotype observed in native W303 background (bud4), but not in W303 BUD4+ | Voth WP, et al. (2005) PMID:15947194 | |
| competitive fitness: decreased | competitive growth fitness profiling of essential genes using hypomorphic DAmP alleles | reduction of function | S288C | Media: minimal medium Details: Relative fitness score: 0.998 | Breslow DK, et al. (2008) PMID:18622397 | |
| haploinsufficient | heterozygous diploid, competitive growth genome-wide fitness profiling | null Allele: hym1-Δ | S288C | Media: turbidostat growth in FPM medium Details: Relative growth score: -0.0046 | Pir P, et al. (2012) PMID:22244311 | |
| haploinsufficient | heterozygous diploid, systematic mutation set | null Allele: hym1-Δ | S288C | Ohnuki S and Ohya Y (2018) PMID:29768403 |
This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).
Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.
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