Phenotype Help

TCD2 / YKL027W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.



Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

17 entries for 11 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
auxotrophy
homozygous diploid, systematic mutation setnull
Allele: tcd2-Δ
S288C myo-inositolVilla-García MJ, et al. (2011) PMID:21136082
chemical compound accumulation: decreased
classical geneticsunspecifiedS288C sterolDetails: upc2-1 mutant background; transposon insertion; tritium suicide selection
Sullivan DP, et al. (2009) PMID:19060182
competitive fitness: decreased
competitive growth

fitness profiling using complete deletion alleles

null
Allele: tcd2-Δ
S288CMedia: minimal medium
Details: Relative fitness score: 0.977
Breslow DK, et al. (2008) PMID:18622397
competitive fitness: decreased
systematic mutation setnull
Allele: tcd2-Δ
S288CMedia: glycerol medium, YPG
Qian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: tcd2-Δ
S288CMedia: rich medium (YPD) w/6% ethanol, ETH
Qian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: tcd2-Δ
S288CMedia: synthetic complete medium, SC
Qian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: tcd2-Δ
S288CMedia: synthetic oak exudate medium, OAK
Qian W, et al. (2012) PMID:23103169
heat sensitivity: increased
homozygous diploid, systematic mutation set

pooled screening for fitness defects at 37 deg C relative to 30 deg C

null
Allele: tcd2-Δ
S288CTemperature: elevated temperature, 37 °C
Sinha H, et al. (2008) PMID:18780730
invasive growth: increased
homozygous diploid, systematic mutation setoverexpressionSigma1278bMedia: nitrogen-sufficient medium
Details: agar invasion score: 0.99; enhanced pseudohyphal growth, based on elevated invasiveness
Shively CA, et al. (2013) PMID:23410832
oxidative stress resistance: increased
homozygous diploid, competitive growthnull
Allele: tcd2-Δ
S288C3 mM hydrogen peroxideBrown JA, et al. (2006) PMID:16738548
Showing 1 to 10 of 17 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


Reset

Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.


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