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SSL2 / YIL143C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

LOM3 , RAD25 12
Protein Product
TFIIH/NER complex ATPase/helicase subunit SSL2
Feature Type
ORF , Verified
Component of RNA polymerase transcription factor TFIIH holoenzyme; acts as dsDNA-dependent translocase in context of TFIIH, unwinds DNA strands during initiation and promotes transcription start site (TSS) scanning; has DNA-dependent ATPase/helicase activity; interacts functionally with TFIIB, has roles in TSS selection and gene looping to juxtapose initiation and termination regions; involved in DNA repair; relocalizes to cytosol under hypoxia; homolog of human ERCC3 2 3 4 5 6 7 8
EC Number