Phenotype Help

MDM31 / YHR194W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.


Summary
Non-essential gene; null mutants have large, spherical mitochondria, decreased mitophagy, can not grow on non-fermentable carbon sources, decreased accumulation of mitochondrial membrane components, such as cardiolipin and phosphatidylethanolamine

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

48 entries for 24 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
cell cycle progression in G1 phase: increased duration
homozygous diploid, systematic mutation setnull
Allele: mdm31-Δ
S288CDetails: percentage of G1 cells greater than two standard deviations (41.57%) above wild type when assayed by FACS
Hoose SA, et al. (2012) PMID:22438835
chemical compound accumulation: decreased
classical geneticsnull
Allele: mdm31-Δ
Other phosphatidylethanolamineDetails: decreased in mitochondria
Osman C, et al. (2009) PMID:19221197
chemical compound accumulation: decreased
classical geneticsnull
Allele: mdm31-Δ
Other cardiolipinDetails: decreased in mitochondria
Osman C, et al. (2009) PMID:19221197
chemical compound accumulation: decreased
homozygous diploidnull
Allele: mdm31-Δ
S288C0.1 mM potassium tellurite, tellurium atomOttosson LG, et al. (2010) PMID:20675578
chemical compound accumulation: increased
homozygous diploid, systematic mutation set

glycogen accumulation in diploid mutant strains grown in microtiter plates

null
Allele: mdm31-Δ
S288C glycogenWilson WA, et al. (2002) PMID:12096123
competitive fitness: decreased
homozygous diploid, competitive growth

genome-wide fitness profiling

null
Allele: mdm31-Δ
S288CMedia: YPD
Details: Relative fitness score: 0.843
Deutschbauer AM, et al. (2005) PMID:15716499
competitive fitness: decreased
systematic mutation setnull
Allele: mdm31-Δ
S288C ethanolQian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: mdm31-Δ
S288CMedia: glycerol medium, YPG
Qian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: mdm31-Δ
S288CMedia: rich medium (YPD) w/6% ethanol, ETH
Qian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: mdm31-Δ
S288CMedia: synthetic complete medium, SC
Qian W, et al. (2012) PMID:23103169
Showing 1 to 10 of 48 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


Reset

Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.


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