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DNA2 / YHR164C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

Protein Product
bifunctional ATP-dependent DNA helicase/ssDNA endodeoxyribonuclease DNA2
Feature Type
ORF , Verified
Tripartite DNA replication factor; single-stranded DNA-dependent ATPase, ATP-dependent nuclease, helicase; tracking protein for flap cleavage during Okazaki fragment maturation; involved in DNA repair/processing of meiotic DNA double strand breaks; component of telomeric chromatin with cell-cycle dependent localization; required for telomerase-dependent telomere synthesis; forms nuclear foci upon DNA replication stress; human homolog DNA2 complements yeast dna2 mutant 2 3 4 5 6 7 8 9 10 11 12 13 14
EC Number