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RTT107 / YHR154W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

ESC4 8
Feature Type
ORF , Verified
BRCA1 C-terminal domain protein needed for recovery from DNA damage; implicated in Mms22-dependent DNA repair during S phase; involved in recruiting SMC5/6 complex to double-strand breaks; DNA damage induces phosphorylation by Mec1p at one or more SQ/TQ motifs; interacts with Mms22p and Slx4p; has four BRCT domains; has a role in regulation of Ty1 transposition; relative distribution to nuclear foci increases upon DNA replication stress 1 2 3 4 5 6 7