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SET1 / YHR119W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
YTX1 , KMT2 8
Protein Product
histone methyltransferase SET1
Feature Type
ORF , Verified
Description
Histone methyltransferase, subunit of the COMPASS (Set1C) complex; COMPASS methylates histone H3K4; Set1p-dependent H3K4 trimethylation recruits Nrd1p, allowing efficient termination of snoRNAs and cryptic unstable transcripts (CUTs) by Nrd1p-Nab3p-Sen1p pathway; modulates histone acetylation levels in promoter proximal regions to ensure efficient Nrd1p-dependent termination; required in transcriptional silencing near telomeres and at silent mating type loci; has a SET domain 2 3 4 5 6 7
EC Number
2.1.1.43

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