ORC6 / YHR118C Homology
- Standard Name
- ORC6 1
- Systematic Name
- YHR118C
- SGD ID
- SGD:S000001160
- Feature Type
- ORF , Verified
- Description
- Subunit of the origin recognition complex (ORC); ORC directs DNA replication by binding to replication origins and is also involved in transcriptional silencing; phosphorylated by Cdc28p; mutation in the human Orc6p is linked to Meier-Gorlin syndrome 2 3 5
- Name Description
- Origin Recognition Complex 4
- Comparative Info
-
Homologs
Homology calls are sourced from the Alliance of Genome Resources. Many aspects of data integration presented at the Alliance require a common set of orthology relationships among genes for the organisms represented, including human. The Alliance provides the results of all methods that have been benchmarked by the Quest for Orthologs Consortium (QfO). The homolog inferences from the different methods have been integrated using the DRSC Integrative Ortholog Prediction Tool (DIOPT), which integrates a number of existing methods including those used by the Alliance: Ensembl Compara, HGNC, Hieranoid, InParanoid, OMA, OrthoFinder, OrthoInspector, PANTHER, PhylomeDB, Roundup, TreeFam, and ZFIN.
0 entries for 0 homologsIncrease the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through its pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table.
Functional Complementation
Information about cross-species functional complementation between yeast and other species, curated by SGD and the Princeton Protein Orthology Database (P-POD).
0 entries for 0 complementsIncrease the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through its pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table.
Fungal Homologs
Fungal Homology calls are sourced from AllianceMine, which compiles fungal homology calls from FungiDB, CGD, Panther, PomBase, TreeFam, HomoloGene, and SGD.
5 entries for 5 homologsIncrease the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through its pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table.
| Species | Gene ID | Gene name | Description | Source |
|---|---|---|---|---|
| S. pombe | SPBC2A9.12 | PomBase | ||
| C. albicans WO-1 | CAWG_01273 | Has domain(s) with predicted DNA binding activity, role in DNA replication and nuclear origin of replication recognition complex localization | CGD | |
| C. dubliniensis CD36 | CD36_00950 | Ortholog(s) have DNA replication origin binding activity and role in DNA replication initiation, chromatin silencing at silent mating-type cassette, pre-replicative complex assembly | CGD | |
| C. parapsilosis CDC317 | CPAR2_109960 | Ortholog(s) have DNA replication origin binding activity and role in DNA replication initiation, chromatin silencing at silent mating-type cassette, pre-replicative complex assembly involved in nuclear cell cycle DNA replication | CGD | |
| C. albicans SC5314 | orf19.3289 | Phosphorylated protein of unknown function | CGD |
External Identifiers
List of external identifiers for the protein from various database sources.
18 entries for 8 sourcesIncrease the total number of rows showing on this page by using the pull-down located below the table, or use the page scroll at the table's top right to browse through its pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table.
| External ID | Source |
|---|---|
| orf19.3289 | CGD |
| 2289 | DIP |
| 6321910 | GenBank/EMBL/DDBJ |
| U00059 | GenBank/EMBL/DDBJ |
| L23323 | GenBank/EMBL/DDBJ |
| AAA21822.1 | GenBank/EMBL/DDBJ |
| AAB68869.1 | GenBank/EMBL/DDBJ |
| 1171922 | GenBank/EMBL/DDBJ |
| 551458 | GenBank/EMBL/DDBJ |
| 529137 | GenBank/EMBL/DDBJ |
Resources
Homologs
AGD | AnalogYeast | BLASTP at NCBI | CGD | FungiDB | PhylomeDB | PomBase | YGOB | YOGY
Protein Databases
AlphaFold Protein Structure | GPMDB | ModelArchive | Pfam domains | SUPERFAMILY | TopologYeast | UniProtKB
Localization
CYCLoPs | dHITS | LoQAtE | YeastGFP | YeastRC Public Images | YeastRGB | YPL+
Post-translational Modifications
CoSMoS.c. | PhosphoGRID | PhosphoPep
S288C only
BLASTN | BLASTP | Design Primers | Restriction Fragment Map | Restriction Fragment Sizes | Six-Frame Translation
S288C vs. other species
BLASTN vs. fungi | BLASTP at NCBI | BLASTP vs. fungi