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DMA1 / YHR115C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
CHF1 4
Protein Product
ubiquitin-conjugating protein DMA1
Feature Type
ORF , Verified
Description
Ubiquitin-protein ligase (E3); controls septin dynamics, spindle position checkpoint (SPOC) with ligase Dma2p by regulating recruitment of Elm1p to bud neck; regulates levels of eIF2 subunit Gcd11p, as well as abundance, localization, and ubiquitination of Cdk inhibitory kinase Swe1p; ubiquitinates cyclin Pcl1p; ortholog of human RNF8, similar to human Chfr; contains FHA, RING fingers; DMA1 has a paralog, DMA2, that arose from the whole genome duplication 1 2 3 4 5 6 7 8
Paralog
DMA2 8
EC Number
2.3.2.27

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