Phenotype Help

MSR1 / YHR091C Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.


Summary
MSR1/YHR091C is a non-essential gene; null mutants are viable but exhibit a range of phenotypic changes including altered metal resistance, absent mitochondrial genome maintenance, absent or decreased respiratory growth rate, decreased cell size, abnormal chemical compound accumulation, decreased chronological lifespan, decreased competitive fitness, increased heat sensitivity, abnormal mitochondrial morphology, increased oxidative stress resistance, altered resistance to chemicals, decreased toxin resistance, decreased utilization of carbon sources, abnormal vacuolar morphology, and decreased vegetative growth rate. Reduction of function mutants show absent mitochondrial genome maintenance and absent respiratory growth.

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

51 entries for 20 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
cell size: decreased
systematic mutation set

analysis of cell size for mutants in the systematic deletion collection

null
Allele: msr1-Δ
S288CDetails: mutant is among the smallest 5% of haploid deletion strains
Jorgensen P, et al. (2002) PMID:12089449
chemical compound accumulation: abnormal
systematic mutation setnull
Allele: msr1-Δ
S288C polyphosphateFreimoser FM, et al. (2006) PMID:17107617
chemical compound accumulation: decreased
homozygous diploid, systematic mutation set

glycogen accumulation in diploid mutant strains grown in microtiter plates

null
Allele: msr1-Δ
S288C glycogenWilson WA, et al. (2002) PMID:12096123
chronological lifespan: decreased
systematic mutation setnull
Allele: msr1-Δ
S288CMarek A and Korona R (2013) PMID:24151994
competitive fitness: decreased
systematic mutation setnull
Allele: msr1-Δ
S288C ethanolQian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: msr1-Δ
S288CMedia: glycerol medium, YPG
Qian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: msr1-Δ
S288CMedia: rich medium (YPD) w/6% ethanol, ETH
Qian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: msr1-Δ
S288CMedia: synthetic complete medium, SC
Qian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: msr1-Δ
S288CMedia: synthetic oak exudate medium, OAK
Qian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: msr1-Δ
S288CMedia: YPD
Qian W, et al. (2012) PMID:23103169
Showing 1 to 10 of 51 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


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