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IRE1 / YHR079C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

ERN1 8
Protein Product
bifunctional endoribonuclease/protein kinase IRE1
Feature Type
ORF , Verified
Serine-threonine kinase and endoribonuclease; transmembrane protein that mediates the unfolded protein response (UPR) by regulating Hac1p synthesis through HAC1 mRNA splicing; role in homeostatic adaptation to ER stress; Kar2p binds inactive Ire1p and releases from it upon ER stress 2 3 4 5 6
EC Number