Literature Help
DYS1 / YHR068W Literature
All manually curated literature for the specified gene, organized by relevance to the gene and by
association with specific annotations to the gene in SGD. SGD gathers references via a PubMed search for
papers whose titles or abstracts contain “yeast” or “cerevisiae;” these papers are reviewed manually and
linked to relevant genes and literature topics by SGD curators.
Primary Literature
Literature that either focuses on the gene or contains information about function, biological role,
cellular location, phenotype, regulation, structure, or disease homologs in other species for the gene
or gene product.
No primary literature curated.
Download References (.nbib)
- Halwas K, et al. (2022) Hypusinated eIF5A Promotes Ribosomal Frameshifting during Decoding of ODC Antizyme mRNA in Saccharomyces cerevisiae. Int J Mol Sci 23(21) PMID:36361762
- Prunetti L, et al. (2016) Deciphering the Translation Initiation Factor 5A Modification Pathway in Halophilic Archaea. Archaea 2016:7316725 PMID:28053595
- Kachroo AH, et al. (2015) Evolution. Systematic humanization of yeast genes reveals conserved functions and genetic modularity. Science 348(6237):921-5 PMID:25999509
- Galvão FC, et al. (2013) The deoxyhypusine synthase mutant dys1-1 reveals the association of eIF5A and Asc1 with cell wall integrity. PLoS One 8(4):e60140 PMID:23573236
- Thompson GM, et al. (2003) Mapping eIF5A binding sites for Dys1 and Lia1: in vivo evidence for regulation of eIF5A hypusination. FEBS Lett 555(3):464-8 PMID:14675757
- Wolff EC and Park MH (1999) Identification of lysine350 of yeast deoxyhypusine synthase as the site of enzyme intermediate formation. Yeast 15(1):43-50 PMID:10028184
- Abid R, et al. (1997) Novel features of the functional site and expression of the yeast deoxyhypusine synthase. Biol Signals 6(3):157-65 PMID:9285099
- Sasaki K, et al. (1996) Deoxyhypusine synthase gene is essential for cell viability in the yeast Saccharomyces cerevisiae. FEBS Lett 384(2):151-4 PMID:8612813
- Kang KR, et al. (1995) Identification of YHR068w in Saccharomyces cerevisiae chromosome VIII as a gene for deoxyhypusine synthase. Expression and characterization of the enzyme. J Biol Chem 270(31):18408-12 PMID:7629166
Related Literature
Genes that share literature (indicated by the purple circles) with the specified gene (indicated by yellow circle).
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Additional Literature
Papers that show experimental evidence for the gene or describe homologs in other species, but
for which the gene is not the paper’s principal focus.
No additional literature curated.
Download References (.nbib)
- Shin BS and Dever TE (2025) Yeast reconstituted translation assays for analysis of eIF5A function. Methods Enzymol 715:155-182 PMID:40382135
- Hofer SJ, et al. (2024) Spermidine is essential for fasting-mediated autophagy and longevity. Nat Cell Biol 26(9):1571-1584 PMID:39117797
- Lanz MC, et al. (2021) In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Rep 22(2):e51121 PMID:33491328
- Rossi D, et al. (2016) Evidence for a Negative Cooperativity between eIF5A and eEF2 on Binding to the Ribosome. PLoS One 11(4):e0154205 PMID:27115996
- Rossi D, et al. (2014) eIF5A has a function in the cotranslational translocation of proteins into the ER. Amino Acids 46(3):645-53 PMID:24306454
- Dias CA, et al. (2013) eIF5A dimerizes not only in vitro but also in vivo and its molecular envelope is similar to the EF-P monomer. Amino Acids 44(2):631-44 PMID:22945904
- Marino SM, et al. (2010) Characterization of surface-exposed reactive cysteine residues in Saccharomyces cerevisiae. Biochemistry 49(35):7709-21 PMID:20698499
- Rintala E, et al. (2009) Low oxygen levels as a trigger for enhancement of respiratory metabolism in Saccharomyces cerevisiae. BMC Genomics 10:461 PMID:19804647
- Jao DL and Chen KY (2006) Tandem affinity purification revealed the hypusine-dependent binding of eukaryotic initiation factor 5A to the translating 80S ribosomal complex. J Cell Biochem 97(3):583-98 PMID:16215987
- Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 PMID:14562095
- Kang KR, et al. (2002) Deoxyhypusine synthase is phosphorylated by protein kinase C in vivo as well as in vitro. Exp Mol Med 34(6):489-95 PMID:12526092
- Lee YB, et al. (1999) Complex formation between deoxyhypusine synthase and its protein substrate, the eukaryotic translation initiation factor 5A (eIF5A) precursor. Biochem J 340 ( Pt 1)(Pt 1):273-81 PMID:10229683
Reviews
No reviews curated.
Download References (.nbib)
- Park MH, et al. (2010) Functional significance of eIF5A and its hypusine modification in eukaryotes. Amino Acids 38(2):491-500 PMID:19997760
- Wolff EC, et al. (2007) Posttranslational synthesis of hypusine: evolutionary progression and specificity of the hypusine modification. Amino Acids 33(2):341-50 PMID:17476569
- Park MH, et al. (1996) The polyamine-derived amino acid hypusine: its post-translational formation in eIF-5A and its role in cell proliferation. Amino Acids 10(2):109-21 PMID:24178473
Gene Ontology Literature
Paper(s) associated with one or more GO (Gene Ontology) terms in SGD for the specified gene.
No gene ontology literature curated.
Download References (.nbib)
- Huh WK, et al. (2003) Global analysis of protein localization in budding yeast. Nature 425(6959):686-91 PMID:14562095
- Kang KR, et al. (1995) Identification of YHR068w in Saccharomyces cerevisiae chromosome VIII as a gene for deoxyhypusine synthase. Expression and characterization of the enzyme. J Biol Chem 270(31):18408-12 PMID:7629166
Interaction Literature
Paper(s) associated with evidence supporting a physical or genetic interaction between the
specified gene and another gene in SGD. Currently, all interaction evidence is obtained from
BioGRID.
No interaction literature curated.
Download References (.nbib)
- Cruz VE, et al. (2024) The DEAD-box ATPase Dbp10/DDX54 initiates peptidyl transferase center formation during 60S ribosome biogenesis. Nat Commun 15(1):3296 PMID:38632236
- Filali-Mouncef Y, et al. (2024) An APEX2-based proximity-dependent biotinylation assay with temporal specificity to study protein interactions during autophagy in the yeast Saccharomyces cerevisiae. Autophagy 20(10):2323-2337 PMID:38958087
- O'Brien MJ and Ansari A (2024) Protein interaction network revealed by quantitative proteomic analysis links TFIIB to multiple aspects of the transcription cycle. Biochim Biophys Acta Proteins Proteom 1872(1):140968 PMID:37863410
- Waltho A, et al. (2024) K48- and K63-linked ubiquitin chain interactome reveals branch- and length-specific ubiquitin interactors. Life Sci Alliance 7(8) PMID:38803224
- Courtin B, et al. (2023) Xrn1 biochemically associates with eisosome proteins after the post diauxic shift in yeast. MicroPubl Biol 2023 PMID:37746059
- Kolhe JA, et al. (2023) The Hsp90 molecular chaperone governs client proteins by targeting intrinsically disordered regions. Mol Cell 83(12):2035-2044.e7 PMID:37295430
- Michaelis AC, et al. (2023) The social and structural architecture of the yeast protein interactome. Nature 624(7990):192-200 PMID:37968396
- Schoppe J, et al. (2020) AP-3 vesicle uncoating occurs after HOPS-dependent vacuole tethering. EMBO J 39(20):e105117 PMID:32840906
- Girstmair H, et al. (2019) The Hsp90 isoforms from S. cerevisiae differ in structure, function and client range. Nat Commun 10(1):3626 PMID:31399574
- Gonzales-Zubiate FA, et al. (2017) Identification of karyopherins involved in the nuclear import of RNA exosome subunit Rrp6 in Saccharomyces cerevisiae. J Biol Chem 292(29):12267-12284 PMID:28539363
- Jungfleisch J, et al. (2017) A novel translational control mechanism involving RNA structures within coding sequences. Genome Res 27(1):95-106 PMID:27821408
- Costanzo M, et al. (2016) A global genetic interaction network maps a wiring diagram of cellular function. Science 353(6306) PMID:27708008
- Jain S, et al. (2016) ATPase-Modulated Stress Granules Contain a Diverse Proteome and Substructure. Cell 164(3):487-98 PMID:26777405
- Galvão FC, et al. (2013) The deoxyhypusine synthase mutant dys1-1 reveals the association of eIF5A and Asc1 with cell wall integrity. PLoS One 8(4):e60140 PMID:23573236
- Willmund F, et al. (2013) The cotranslational function of ribosome-associated Hsp70 in eukaryotic protein homeostasis. Cell 152(1-2):196-209 PMID:23332755
- Sharifpoor S, et al. (2012) Functional wiring of the yeast kinome revealed by global analysis of genetic network motifs. Genome Res 22(4):791-801 PMID:22282571
- Fasolo J, et al. (2011) Diverse protein kinase interactions identified by protein microarrays reveal novel connections between cellular processes. Genes Dev 25(7):767-78 PMID:21460040
- Scherrer T, et al. (2011) Defining potentially conserved RNA regulons of homologous zinc-finger RNA-binding proteins. Genome Biol 12(1):R3 PMID:21232131
- Szappanos B, et al. (2011) An integrated approach to characterize genetic interaction networks in yeast metabolism. Nat Genet 43(7):656-62 PMID:21623372
- Costanzo M, et al. (2010) The genetic landscape of a cell. Science 327(5964):425-31 PMID:20093466
- Kaake RM, et al. (2010) Characterization of cell cycle specific protein interaction networks of the yeast 26S proteasome complex by the QTAX strategy. J Proteome Res 9(4):2016-29 PMID:20170199
- Guerrero C, et al. (2008) Characterization of the proteasome interaction network using a QTAX-based tag-team strategy and protein interaction network analysis. Proc Natl Acad Sci U S A 105(36):13333-8 PMID:18757749
- Tarassov K, et al. (2008) An in vivo map of the yeast protein interactome. Science 320(5882):1465-70 PMID:18467557
- Yu H, et al. (2008) High-quality binary protein interaction map of the yeast interactome network. Science 322(5898):104-10 PMID:18719252
- Ptacek J, et al. (2005) Global analysis of protein phosphorylation in yeast. Nature 438(7068):679-84 PMID:16319894
- Thompson GM, et al. (2003) Mapping eIF5A binding sites for Dys1 and Lia1: in vivo evidence for regulation of eIF5A hypusination. FEBS Lett 555(3):464-8 PMID:14675757
Regulation Literature
Paper(s) associated with one or more pieces of regulation evidence in SGD, as found on the
Regulation page.
No regulation literature curated.
Post-translational Modifications Literature
Paper(s) associated with one or more pieces of post-translational modifications evidence in SGD.
No post-translational modifications literature curated.
Download References (.nbib)
- Leutert M, et al. (2023) The regulatory landscape of the yeast phosphoproteome. Nat Struct Mol Biol 30(11):1761-1773 PMID:37845410
- Lanz MC, et al. (2021) In-depth and 3-dimensional exploration of the budding yeast phosphoproteome. EMBO Rep 22(2):e51121 PMID:33491328
- Zhou X, et al. (2021) Cross-compartment signal propagation in the mitotic exit network. Elife 10 PMID:33481703
- Swaney DL, et al. (2013) Global analysis of phosphorylation and ubiquitylation cross-talk in protein degradation. Nat Methods 10(7):676-82 PMID:23749301
- Henriksen P, et al. (2012) Proteome-wide analysis of lysine acetylation suggests its broad regulatory scope in Saccharomyces cerevisiae. Mol Cell Proteomics 11(11):1510-22 PMID:22865919
Functional Complementation Annotations Literature
Paper(s) associated with one or more pieces of functional complementation annotations evidence in SGD.
No functional complementation annotations literature curated.
High-Throughput Literature
Paper(s) associated with one or more pieces of high-throughput evidence in SGD.
No high-throughput literature curated.
Download References (.nbib)
- Forster DT, et al. (2022) BIONIC: biological network integration using convolutions. Nat Methods 19(10):1250-1261 PMID:36192463
- Halwas K, et al. (2022) Hypusinated eIF5A Promotes Ribosomal Frameshifting during Decoding of ODC Antizyme mRNA in Saccharomyces cerevisiae. Int J Mol Sci 23(21) PMID:36361762
- Ohnuki S and Ohya Y (2018) High-dimensional single-cell phenotyping reveals extensive haploinsufficiency. PLoS Biol 16(5):e2005130 PMID:29768403
- Vizoso-Vázquez A, et al. (2012) Ixr1p and the control of the Saccharomyces cerevisiae hypoxic response. Appl Microbiol Biotechnol 94(1):173-84 PMID:22189861
- Venters BJ, et al. (2011) A comprehensive genomic binding map of gene and chromatin regulatory proteins in Saccharomyces. Mol Cell 41(4):480-92 PMID:21329885
- Cipollina C, et al. (2008) Saccharomyces cerevisiae SFP1: at the crossroads of central metabolism and ribosome biogenesis. Microbiology (Reading) 154(Pt 6):1686-1699 PMID:18524923
- Yu L, et al. (2006) A survey of essential gene function in the yeast cell division cycle. Mol Biol Cell 17(11):4736-47 PMID:16943325
- Lum PY, et al. (2004) Discovering modes of action for therapeutic compounds using a genome-wide screen of yeast heterozygotes. Cell 116(1):121-37 PMID:14718172
- Giaever G, et al. (2002) Functional profiling of the Saccharomyces cerevisiae genome. Nature 418(6896):387-91 PMID:12140549