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ERG11 / YHR007C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
CYP51 17
Protein Product
sterol 14-demethylase
Feature Type
ORF , Verified
Description
Lanosterol 14-alpha-demethylase; catalyzes C-14 demethylation of lanosterol to form 4,4''-dimethyl cholesta-8,14,24-triene-3-beta-ol in ergosterol biosynthesis pathway; transcriptionally down-regulated when ergosterol is in excess; member of cytochrome P450 family; associated and coordinately regulated with the P450 reductase Ncp1p; human CYP51A1 functionally complements the lethality of the erg11 null mutation 2 3 4 5 6 7 8 9
EC Number
1.14.14.154

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