Sequence Help

GPA1 / YHR005C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

CDC70 26 , DAC1 27 , SCG1 8
Protein Product
guanine nucleotide-binding protein subunit alpha
Feature Type
ORF , Verified
Subunit of G protein involved in pheromone response; GTP-binding alpha subunit of heterotrimeric G protein; negatively regulates mating pathway by sequestering G(beta)gamma and triggering an adaptive response; activates Vps34p at endosome; protein abundance increases in response to DNA replication stress; mutations in human homolog GNAS associated with McCune-Albright syndrome 2 3 4 5 6