SNF6 / YHL025W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

SNF6/YHL025W is a non-essential gene, null mutants are viable, grow slowly, and exhibit a range of phenotypic abnormalities including decreased resistance to alkaline pH, indicating impaired ability to survive in high pH environments; decreased budding index and increased duration of cell cycle progression in G1, suggesting disruptions in cell division and growth; shortened chronological lifespan; heightened cold sensitivity, making these mutants more vulnerable to low temperatures; diminished competitive fitness, indicating reduced viability in competitive conditions; decreased desiccation resistance, indicating reduced viability in dry conditions; impaired endocytosis, suggesting difficulties in cellular uptake; increased heat sensitivity, suggesting heightened vulnerability to high temperatures; decreased resistance to hydrostatic pressure; reduced mating efficiency and sporulation, affecting reproductive success; decreased mitotic recombination and transposable element transposition, affecting genomic dynamics; slow respiratory growth; decreased UV resistance; and abnormal vacuolar morphology, which could affect cellular storage and organization. Overexpression of SNF6 affects gene silencing and slows growth.

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources