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UBP3 / YER151C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

BLM3 17
Protein Product
mRNA-binding ubiquitin-specific protease UBP3
Feature Type
ORF , Verified
Ubiquitin-specific protease that cleaves Ub-protein fusions; interacts with cofactor Bre5p to regulate transport between ER and Golgi, deubiquitinating COPII and COPI proteins, Sec23p and Sec27p; mediates steady-state retention of Golgi membrane proteins with Bre5p; phosphorylation (S695) by Hog1p regulates transcriptional activation by osmostress; inhibits Ras/PKA signaling through Ira2p; inhibits silencing; role in ribophagy; protein abundance increases in response to DNA replication stress 1 2 3 4 5 6 7 8 9 10
EC Number