Phenotype Help

AIM9 / YER080W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.


Summary
Non-essential gene; null mutant displays increased competitive fitness in minimal medium; null mutant has a reduced frequency of spontaneous mitochondrial genome loss; null mutant displays decreased accumulation of zinc and copper cations but increased accumulation of potassium ions; heterozygous diploid null has decreased starvation resistance after low nutrient stress and is haploproficient

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

15 entries for 12 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
cell death: absent
classical geneticsnull
Allele: aim9-Δ
S288CTreatment: human caspase-10
Lisa-Santamaría P, et al. (2012) PMID:22782902
chemical compound accumulation: decreased
systematic mutation setnull
Allele: aim9-Δ
S288C copper cationYu D, et al. (2012) PMID:23151179
chemical compound accumulation: decreased
systematic mutation setnull
Allele: aim9-Δ
S288C zinc cationYu D, et al. (2012) PMID:23151179
chemical compound accumulation: increased
systematic mutation setnull
Allele: aim9-Δ
S288C potassium(1+)Yu D, et al. (2012) PMID:23151179
chronological lifespan: decreased
systematic mutation set null
Allele: aim9-Δ
S288CCampos SE, et al. (2018) PMID:29575540
competitive fitness: increased
competitive growth

fitness profiling using complete deletion alleles

null
Allele: aim9-Δ
S288CMedia: minimal medium
Details: Relative fitness score: 1.006
Breslow DK, et al. (2008) PMID:18622397
haploproficient
heterozygous diploid, competitive growth

genome-wide fitness profiling

null
Allele: aim9-Δ
S288CMedia: turbidostat growth in FPM medium
Details: Relative growth score: 0.0054
Pir P, et al. (2012) PMID:22244311
mitochondrial genome maintenance: abnormal
large-scale surveynull
Allele: aim9-Δ
S288CDetails: decreased frequency of spontaneous mitochondrial genome loss
Hess DC, et al. (2009) PMID:19300474
protein/peptide accumulation: increased
Reporter: Rnr3p
systematic mutation setnull
Allele: fmp29-Δ
S288CHendry JA, et al. (2015) PMID:25721128
resistance to chemicals: decreased
systematic mutation setnull
Allele: aim9-Δ
S288C15 ug/ml 5-fluorouracilGustavsson M and Ronne H (2008) PMID:18314501
Showing 1 to 10 of 15 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


Reset

Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.


Resources