Phenotype Help

MNN1 / YER001W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.



Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

15 entries for 11 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
auxotrophy
classical geneticsunspecifiedX2180-1AMedia: adenine
Raschke WC, et al. (1973) PMID:4578088
chemical compound accumulation: increased
homozygous diploid null
Allele: mnn1-Δ
S288C reactive oxygen speciesTreatment: cobalt dichloride, 1 mM
Details: increased intracellular accumulation of ROS in cells treated with CoCl2 for 12 hrs; possible defect in scavenging oxidative stress
Zhao YY, et al. (2020) PMID:31904504
competitive fitness: decreased
systematic mutation setnull
Allele: mnn1-Δ
S288CMedia: synthetic complete medium, SC
Qian W, et al. (2012) PMID:23103169
competitive fitness: increased
competitive growth

fitness profiling using complete deletion alleles

null
Allele: mnn1-Δ
S288CMedia: minimal medium
Details: Relative fitness score: 1.002
Breslow DK, et al. (2008) PMID:18622397
haploproficient
heterozygous diploid, competitive growth

genome-wide fitness profiling

null
Allele: mnn1-Δ
S288CMedia: turbidostat growth in FPM medium
Details: Relative growth score: 0.0044
Pir P, et al. (2012) PMID:22244311
killer toxin resistance: increased
systematic mutation setnull
Allele: mnn1-Δ
S288CDetails: K28 killer toxin
Carroll SY, et al. (2009) PMID:19853568
liquid culture appearance: abnormal
classical geneticsunspecifiedX2180-1ATreatment: adsorbed S. cerevisiae X2180 antiserum, 1:20 dilution
Details: decreased agglutination
Raschke WC, et al. (1973) PMID:4578088
replicative lifespan: increased
classical geneticsnull
Allele: mnn1-Δ
S288CMcCormick MA, et al. (2015) PMID:26456335
resistance to chemicals: decreased
classical geneticsunspecifiedOther50 ug/ml hygromycin BDean N (1995) PMID:7877969
resistance to chemicals: decreased
heterozygous diploid, systematic mutation set null
Allele: mnn1-Δ
S288C75 μg/mL flurbiprofenLum PY, et al. (2004) PMID:14718172
Showing 1 to 10 of 15 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


Reset

Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.


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