CDC39 / YCR093W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.

Summary

Essential gene; conditional mutant arrests in the G1 phase at START, as conjugation-competent, unbudded cells with single, undivided nuclei and pear-shaped morphology; conditional mutant displays elevated colony sectoring indicative of chromosomal instability and increased nucleolar size; homozygous diploid transposon insertion mutant is unable to undergo nitrogen-starvation induced pseudohyphal growth; heterozygous diploid null mutant has increased innate thermotolerance; overexpression results in an accumulation of cells with a 2C DNA content and an increased percentage of large-budded cells indicative of a G2 or M phase delay or arrest

Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).

Resources