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ELO2 / YCR034W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
GNS1 7 , VBM2 2 , FEN1 8
Protein Product
fatty acid elongase ELO2
Feature Type
ORF , Verified
Description
Fatty acid elongase, involved in sphingolipid biosynthesis; acts on fatty acids of up to 24 carbons in length; mutations have regulatory effects on 1,3-beta-glucan synthase, vacuolar ATPase, and the secretory pathway; ELO2 has a paralog, ELO1, that arose from the whole genome duplication; lethality of the elo2 elo3 double null mutation is functionally complemented by human ELOVL1 and weakly complemented by human ELOVL3 or ELOV7 1 2 3 4 5 6
Paralog
ELO1 5
EC Number
2.3.1.199

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