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CIT2 / YCR005C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Protein Product
citrate (Si)-synthase CIT2
Feature Type
ORF , Verified
Description
Citrate synthase, peroxisomal isozyme involved in glyoxylate cycle; catalyzes condensation of acetyl coenzyme A and oxaloacetate to form citrate; expression is controlled by Rtg1p and Rtg2p transcription factors; SCF-Ucc1 regulates level of Cit2p to maintain citrate homeostasis; oxaloacetate-dependent positive feedback loop inhibits Cit2p ubiquitination; CIT2 has a paralog, CIT1, that arose from the whole genome duplication 1 2 3 4 5
Paralog
CIT1 5
EC Number
2.3.3.16

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