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PDI1 / YCL043C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
MFP1 , TRG1
Protein Product
protein disulfide isomerase PDI1
Feature Type
ORF , Verified
Description
Protein disulfide isomerase; multifunctional oxidoreductase of the ER lumen, essential for disulfide bond formation in secretory and cell-surface proteins, processing of non-native disulfide bonds; Ero1p activator; complexes with exomannosidase, Mnl1p to facilitate the recognition of misfolded glycoproteins and the trimming of glycan Man8GlcNAc2 to Man7GlcNAc2 on substrates, thereby accelerating ERAD; PDI1 has a paralog, EUG1, that arose from the whole genome duplication 1 2 3 4 6 7 8 9
Paralog
EUG1 9
EC Number
5.3.4.1

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