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ISW1 / YBR245C Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.


Aliases
SGN2 7
Protein Product
chromatin-remodeling ATPase ISW1
Feature Type
ORF , Verified
Description
ATPase subunit of imitation-switch (ISWI) class chromatin remodelers; with Ioc3p forms Isw1a complex involved in repression of transcription initiation; with Ioc2p and Ioc4p forms Isw1b complex involved in regulation of transcription elongation; Isw1b recruited to ORFs by H3K36 methylation and acts with Chd1p to prevent trans-histone exchange over coding regions; Isw1p import into nucleus depends on C-terminal bipartite nuclear targeting signal KRIR X19 KKAK 1 2 3 4 5 6

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