Sequence Help

ATG12 / YBR217W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

APG12 4
Feature Type
ORF , Verified
Ubiquitin-like modifier involved in autophagy and the Cvt pathway; conserved; conjugated to Atg5p to form a complex involved in Atg8p lipidation; Atg5p-Atg12p conjugate enhances E2 activity of Atg3p by rearranging its catalytic site, also forms a complex with Atg16p; the Atg5-Atg12/Atg16 complex binds to membranes and is essential for autophagosome formation; homolog of mammalian ULK1 2 3 4 5 6 7 8 9 10