Sequence Help

CKS1 / YBR135W Sequence

Sequences and genome annotation information for Reference Strain S288C and a select set of Alternative References.

Protein Product
cyclin-dependent protein kinase regulatory subunit CKS1
Feature Type
ORF , Verified
Cyclin-dependent protein kinase regulatory subunit and adaptor; interacts with Cdc28p (aka Cdk1p); required for G1/S and G2/M phase transitions and budding; mediates phosphorylation and degradation of Sic1p; modulates proteolysis of M-phase targets through interactions with the proteasome; role in transcriptional regulation, recruiting proteasomal subunits to target gene promoters; human homologs CKS1B and CKS2 can each complement yeast cks1 null mutant 1 2 3 4 5 6 7