Sequence Help
CKS1 / YBR135W Sequence
Sequences and genome annotation information for Reference Strain S288C and a select set of
Alternative References.
- Protein Product
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cyclin-dependent protein kinase regulatory subunit CKS1
- Feature Type
- ORF
, Verified
- Description
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Cyclin-dependent protein kinase regulatory subunit and adaptor; interacts with Cdc28p (aka Cdk1p); required for G1/S and G2/M phase transitions and budding; mediates phosphorylation and degradation of Sic1p; modulates proteolysis of M-phase targets through interactions with the proteasome; role in transcriptional regulation, recruiting proteasomal subunits to target gene promoters; human homologs CKS1B and CKS2 can each complement yeast cks1 null mutant
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