Phenotype Help

MIS1 / YBR084W Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.



Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

20 entries for 13 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
cell cycle progression in G1 phase: increased duration
homozygous diploid, systematic mutation setnull
Allele: mis1-Δ
S288CDetails: percentage of G1 cells greater than two standard deviations (41.57%) above wild type when assayed by FACS
Hoose SA, et al. (2012) PMID:22438835
competitive fitness: decreased
competitive growth

fitness profiling using complete deletion alleles

null
Allele: mis1-Δ
S288CMedia: minimal medium
Details: Relative fitness score: 0.991
Breslow DK, et al. (2008) PMID:18622397
competitive fitness: decreased
systematic mutation setnull
Allele: mis1-Δ
S288C ethanolQian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: mis1-Δ
S288CMedia: glycerol medium, YPG
Qian W, et al. (2012) PMID:23103169
competitive fitness: increased
systematic mutation setnull
Allele: mis1-Δ
S288CMedia: synthetic oak exudate medium, OAK
Qian W, et al. (2012) PMID:23103169
desiccation resistance: decreased
homozygous diploid, systematic mutation setnull
Allele: mis1-Δ
S288CTreatment: pooled mutants subject to three cycles of growth to post-diauxic phase followed by desiccation and regrowth
Details: 2-fold or greater decreased survival after the treatment
Ratnakumar S, et al. (2011) PMID:20963216
oxidative stress resistance: increased
competitive growth null
Allele: mis1-Δ
S288C1 mM paraquatHelsen J, et al. (2020) PMID:32658971
protein/peptide accumulation: decreased
Reporter: Arg8m
systematic mutation set null
Allele: mis1-Δ
S288CDetails: reduced expression of Arg8m, a synthetic Arg8p adapted to the mitochondrial genetic code and integrated into the mtDNA, after curing and mtDNA cytoduction; mutants maintain mtDNA but are defective in the expression of mitochondrially-encoded proteins
Stenger M, et al. (2020) PMID:32904421
resistance to chemicals: decreased
systematic mutation setnull
Allele: mis1-Δ
S288C0.1% oleateLockshon D, et al. (2007) PMID:17151231
resistance to chemicals: decreased
systematic mutation setnull
Allele: mis1-Δ
S288C22 mg/ml amitroleAlamgir M, et al. (2010) PMID:20691087
Showing 1 to 10 of 20 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


Reset

Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.


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