Phenotype Help

TCM62 / YBR044C Phenotype

Phenotype annotations for a gene are curated single mutant phenotypes that require an observable (e.g., "cell shape"), a qualifier (e.g., "abnormal"), a mutant type (e.g., null), strain background, and a reference. In addition, annotations are classified as classical genetics or high-throughput (e.g., large scale survey, systematic mutation set). Whenever possible, allele information and additional details are provided.



Annotations

A phenotype is defined as an observable (e.g., apoptosis) and a qualifier (e.g., increased). There may be more than one row with the same phenotype if that phenotype was observed in separate studies or in different conditions, strains, alleles, etc.

38 entries for 18 phenotypes


Increase the total number of rows showing on this page using the pull-down located below the table, or use the page scroll at the table's top right to browse through the table's pages; use the arrows to the right of a column header to sort by that column; filter the table using the "Filter" box at the top of the table; click on the small "i" buttons located within a cell for an annotation to view further details.

PhenotypeExperiment TypeMutant InformationStrain BackgroundChemicalDetailsReference
biofilm formation: increased
systematic mutation setnull
Allele: tcm62-Δ
Sigma1278bScherz K, et al. (2014) PMID:25009170
chemical compound excretion: increased
classical geneticsnull
Allele: tcm62-Δ
S288C acetic acidRomano JD and Kolter R (2005) PMID:15659672
competitive fitness: decreased
competitive growth

fitness profiling using complete deletion alleles

null
Allele: tcm62-Δ
S288CMedia: minimal medium
Details: Relative fitness score: 0.917
Breslow DK, et al. (2008) PMID:18622397
competitive fitness: decreased
systematic mutation setnull
Allele: tcm62-Δ
S288C ethanolQian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: tcm62-Δ
S288CMedia: glycerol medium, YPG
Qian W, et al. (2012) PMID:23103169
competitive fitness: decreased
systematic mutation setnull
Allele: tcm62-Δ
S288CMedia: synthetic complete medium, SC
Qian W, et al. (2012) PMID:23103169
metal resistance: decreased
homozygous diploid, systematic mutation set null
Allele: tcm62-Δ
S288C5.0 mM gallium(3+)Treatment: gallium trichloride, 5.0 mM
Schulze Y, et al. (2023) PMID:37193668
metal resistance: decreased
homozygous diploid, systematic mutation set null
Allele: tcm62-Δ
S288C2.6 mM indium(3+)Treatment: indium chloride, 2.6 mM
Schulze Y, et al. (2023) PMID:37193668
metal resistance: decreased
homozygous diploid, systematic mutation set null
Allele: tcm62-Δ
S288C200 μM mercury(2+)Treatment: mercury dichloride, 200 μM
Xian J, et al. (2024) PMID:39057376
metal resistance: increased
systematic mutation set null
Allele: tcm62-Δ
S288C lithium(1+)Treatment: lithium chloride, 100 mM
Details: null mutants exhibiting growth between 110-150% growth at 100 mM LiCl were classified as having a medium level of resistance; screen consisted of a 4 step approach including qualitative assessment on Li-agar plates, liquid microplate assessment, tertiary screening in liquid and a quaternary screen using Li2SO4, followed by classification based on the degree of sensitivity
Fierling N, et al. (2024) PMID:38142127
Showing 1 to 10 of 38 entries

Shared Phenotypes

This diagram displays phenotype observables (purple squares) that are shared between the given gene (yellow circle) and other genes (gray circles) based on the number of phenotype observables shared (adjustable using the slider at the bottom).


Reset

Click on a gene or phenotype observable name to go to its specific page within SGD; drag any of the gene or observable objects around within the visualization for easier viewing; click “Reset” to automatically redraw the diagram; filter the genes that share observable terms with the given gene by the number of terms they share by clicking anywhere on the slider bar or dragging the tab to the desired filter number.


Resources